Harriet Seitler is the Co-CEO of SignUp Media, where she is expanding access to entertainment through American Sign Language interpretation and leading partnerships that bring accessible content to Deaf audiences worldwide. She is also the Founder of Really Good Partners and a Founding Partner of Bistro Partners, advising and investing in companies across media, technology, accessibility, and digital innovation.

Previously, Seitler served as Chief Marketing Officer and Executive Vice President of OWN: Oprah Winfrey Network and Harpo Studios, where she led brand strategy, marketing, and audience growth initiatives. She played a key role in developing major initiatives including Oprah.com and The Dr. Oz Show, and contributed to some of the most successful promotional campaigns in The Oprah Winfrey Show history. Earlier in her career, she held leadership roles as Vice President of Marketing and Creative Services at ESPN and Senior Vice President of Marketing and Promotions at MTV.